Body Composition

GHRP-2

Growth Hormone Releasing Peptide-2

Potent GH stimulation with cortisol consideration

Research Status: Phase II clinical trials (Japan: approved as diagnostic agent) KP-102 Pralmorelin
Mechanism of Action

How it works

GHRP-2 acts on both the pituitary and hypothalamus to amplify GH secretion. Unlike Ipamorelin, it also causes some elevation of cortisol and prolactin at higher doses via its ghrelin receptor activity.

Areas of Research

What the research explores

In published research, GHRP-2 has been studied in connection with the following. These describe findings reported in the literature — not approved uses, claims, or outcomes to expect.

  • Strong GH pulse stimulation
  • Promotes lean muscle development
  • Enhances fat metabolism
  • Cardioprotective properties in research
  • Neuroprotective effects observed in animal models
  • Improves healing and recovery
Research Highlight

GHRP-2 has been studied extensively since the 1980s and is approved in Japan as a diagnostic agent for GH deficiency, making it one of the most clinically validated GHSs.

Safety Profile

Adverse events & gaps

Dose-dependent cortisol and prolactin elevation. May increase hunger. Generally well-tolerated in short-term studies.



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