01 / 06
BPC-157
Body Protection Compound 157
A 15-amino-acid stable gastric peptide with extensive regenerative research across tendon, ligament, and gut healing models.
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Evidence-based education on the peptides reshaping modern wellness, recovery, and longevity research.
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Pick a focus area and jump straight to the relevant peptides.
Body Composition
Fat loss, lean mass, GH support
Healing & Recovery
Tissue repair, anti-inflammatory
Cognitive
Memory, focus, neuroprotection
Anti-Aging
Longevity & cellular repair
Immune Support
Thymic & antimicrobial
Skin & Hair
Collagen & follicle health
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Eight Research
Domains. One Platform.
Body Composition
Growth hormone secretagogues, fat-targeting fragments, and GHRH analogs studied for lean mass, lipolysis, and metabolic optimization.
Explore category
Healing & Recovery
Tissue repair, anti-inflammatory, and angiogenic peptides.
Cognitive Enhancement
Neuropeptides for memory, focus, and neuroplasticity.
Anti-Aging & Longevity
Telomere, mitochondrial, and bioregulator peptides.
Immune Support
Thymic and antimicrobial peptides for immune modulation.
Skin & Hair
Copper peptides and growth factors for dermal repair.
Featured Compounds
Six peptides
Six peptides
worth knowing.
Keep scrolling to move through the most clinically significant peptides in our reference library. Each represents a distinct mechanism, research status, and therapeutic domain.
02 / 06
Epithalon
Ala-Glu-Asp-Gly
Tetrapeptide that activates telomerase and extends telomere length — the most-studied longevity peptide globally.
03 / 06
Tesamorelin
Egrifta
Synthetic GHRH analog and the only FDA-approved peptide for visceral fat reduction in HIV-associated lipodystrophy.
04 / 06
Semax
ACTH 4-7 Pro-Gly-Pro
Russia's premier cognitive enhancement peptide. Upregulates BDNF expression and improves memory consolidation.
05 / 06
Thymosin α-1
Zadaxin
Immune-modulating peptide approved in 37+ countries for hepatitis B/C and as cancer adjunct therapy.
06 / 06
GHK-Cu
Copper Peptide GHK-Cu
Copper-binding tripeptide that triggers tissue remodeling, stimulates collagen synthesis, and resets aged cells.
A
Alanine
R
Arginine
N
Asparagine
D
Aspartate
C
Cysteine
E
Glutamate
Q
Glutamine
G
Glycine
H
Histidine
I
Isoleucine
L
Leucine
K
Lysine
M
Methionine
F
Phenylalanine
P
Proline
S
Serine
T
Threonine
W
Tryptophan
Y
Tyrosine
V
Valine
How Peptides
Work
Peptides are short chains of amino acids that act as precise signaling molecules. Unlike broad-spectrum drugs, they interact with specific receptors to direct targeted biological responses.
Gly
Pro
Arg
Lys
Ala
Val
Leu
Phe
Thr
Ser
Asn
Gln
Each node represents an amino acid in a peptide chain.
01 / Structure
Amino Acid Sequences with Biological Precision
Peptides are defined as chains of 2 to 50 amino acids linked by peptide bonds. Their sequence determines their three-dimensional structure, which in turn determines which receptors they can bind. This specificity is why peptides can produce targeted effects that broad-molecule drugs often cannot.
02 / Signaling
Receptor Binding and Downstream Cascades
When a peptide binds to its target receptor, it initiates signaling cascades: phosphorylation events, gene transcription changes, enzyme activation, or ion channel modulation. Growth hormone secretagogues, for example, bind GHS-R1a receptors on pituitary cells to trigger GH pulse amplification via cyclic AMP.
03 / Endogenous Origins
Many Are Derived from Naturally Occurring Compounds
Most research peptides are derived from or modeled after peptides the human body naturally produces. BPC-157 comes from a gastric protein; Epithalon from the pineal gland; GHK-Cu from human plasma. This endogenous basis often correlates with favorable safety profiles relative to synthetic drugs.
04 / Research Status
From Preclinical Models to Clinical Trials
Peptide research spans a spectrum: from in vitro cell studies, through animal models, to Phase I-III human clinical trials. Some peptides have reached FDA approval (Tesamorelin, Bremelanotide), while others have regulatory approval in specific countries. Understanding a peptide's research status is essential for accurate risk assessment.
05 / Stability & Delivery
Administration Routes and Bioavailability Considerations
Most peptides are rapidly degraded by gastrointestinal enzymes, making oral bioavailability a challenge. Research primarily uses subcutaneous or intramuscular injection for systemic action. Exceptions include KPV (orally stable), Dihexa (lipophilic, crosses BBB), and intranasal peptides like Semax and Selank. Delivery technology continues to advance.
Research Highlights
Landmark Peptides
Worth Knowing
Healing & Recovery
BPC-157
Body Protection Compound-157 • 15 amino acids
Derived from a protective protein in human gastric juice, BPC-157 is among the most researched regenerative peptides. It promotes angiogenesis, modulates the nitric oxide system, and has demonstrated healing acceleration across tendon, ligament, gut, and neural tissue in extensive preclinical research.
- Accelerates tendon and ligament healing
- Protects gastrointestinal mucosa
- Anti-inflammatory and neuroprotective
- Promotes new blood vessel formation
Preclinical
Body Composition
CJC-1295
Long-acting GHRH analog that amplifies growth hormone pulses for 6+ days per injection. Phase II clinical data confirms 2-10x GH elevation. Frequently studied with Ipamorelin for additive effects.
Phase II
Anti-Aging & Longevity
Epithalon
Tetrapeptide from the bovine pineal gland with 15+ years of Russian clinical data. Activates telomerase, restores melatonin production in elderly subjects, and has demonstrated lifespan extension in multiple animal models.
Human Data
Why Peptide Science
Is Rapidly Advancing
Peptides occupy a unique space in biomedical research: highly specific, naturally derived, and increasingly clinically validated.
Receptor Specificity
Peptides bind to specific receptors with high selectivity, producing targeted biological effects that broad-spectrum drugs cannot achieve. This selectivity often translates to fewer off-target side effects.
Endogenous Origins
Many research peptides are modifications of peptides the body naturally produces. This endogenous basis often confers biological compatibility and reduces the risk of immune rejection or foreign-molecule reactions.
Diverse Mechanisms
Peptides can activate receptors, inhibit enzymes, modulate gene expression, or act as neurotransmitters. This mechanistic diversity makes them applicable across virtually every organ system in the body.
Gene-Level Effects
Certain peptides, like GHK-Cu and Epithalon, operate at the genomic level, resetting gene expression patterns toward healthier states. This represents a fundamentally different class of intervention than conventional pharmacology.
Growing Clinical Base
From Tesamorelin's FDA approval for body composition to Thymosin Alpha-1's use in 37 countries, peptides are graduating from preclinical research to approved therapeutics at an accelerating pace.
Metabolic Degradation
Unlike small molecules that accumulate, peptides are metabolized into constituent amino acids. This metabolic pathway eliminates the accumulation toxicity concerns associated with many conventional drugs.
Browse the
Peptide Library
Body Composition
Ipamorelin
The most selective GH secretagogue
Cognitive Enhancement
Semax
Russia's premier cognitive enhancement peptide
Skin & Hair
GHK-Cu
Copper-bound peptide that resets tissue to a younger state
Immune Support
Thymosin Alpha-1
The thymus gland's master immune modulator
Anti-Aging & Longevity
Epithalon
Telomerase-activating peptide with longevity research
Cognitive Enhancement
Selank
Anxiolytic and nootropic with immune modulation
Healing & Recovery
TB-500
Systemic healing and anti-inflammatory signaling
Body Composition
Tesamorelin
The only FDA-approved peptide for visceral fat reduction
Sleep & Recovery
DSIP
Sleep architecture regulation and stress resilience
Sexual Health
PT-141
FDA-approved centrally-acting sexual dysfunction treatment
Anti-Aging & Longevity
Humanin
Mitochondrial peptide protecting against neurodegeneration and aging
Healing & Recovery
KPV
Potent anti-inflammatory with gut healing and skin repair properties
Use the arrows to browse. Click any card for the full research profile.
From the Axiom Labz Shop
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Third-party tested, batch-specific COAs, HPLC purity verification. Browse the full catalog on the Axiom Labz store.
10mg
Tirzepatide
Dual GIP/GLP-1 receptor agonist
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Thymosin Alpha-1
Immune-modulating thymic peptide
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20mg
TB-500 / BPC-157
Synergistic recovery blend
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10mg
Tesamorelin
GHRH analog for visceral fat
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For research use only. Not for human consumption.
Latest Research
Peer-Reviewed
Full research database
Peer-Reviewed
Evidence
New England Journal of Medicine
Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1)
In this 68-week, double-blind, randomized trial of 1,961 adults, once-weekly semaglutide 2.4 mg produced a mean body-weight reduction of 14.9% versus 2.4% with placebo, alongside improvements in cardiometabolic risk factors.
New England Journal of Medicine
Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1)
A 72-week phase 3 trial of 2,539 adults without diabetes; the dual GIP/GLP-1 receptor agonist tirzepatide achieved mean weight reductions of up to 20.9% at the 15 mg dose, the largest yet reported for a pharmacologic agent at the time.
New England Journal of Medicine
Metabolic Effects of a Growth Hormone–Releasing Factor in Patients with HIV
The pivotal trial supporting FDA approval of tesamorelin: in HIV patients with abdominal fat accumulation, tesamorelin significantly reduced visceral adipose tissue and triglycerides over 26 weeks without worsening glucose tolerance.
Obstetrics & Gynecology
Bremelanotide for Hypoactive Sexual Desire Disorder (RECONNECT)
Two phase 3 randomized trials supporting FDA approval of bremelanotide (PT-141): the melanocortin agonist significantly improved sexual desire and reduced associated distress in premenopausal women with HSDD.
The Lancet
Once-Weekly Cagrilintide for Weight Management — A Phase 2 Trial
The long-acting amylin analogue cagrilintide produced dose-dependent weight loss up to 10.8% over 26 weeks in adults with overweight or obesity, supporting amylin agonism as a distinct anti-obesity mechanism.
Cell Metabolism
The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance
The foundational MOTS-c paper: this mitochondrial-derived peptide regulates the folate–AMPK pathway, enhancing insulin sensitivity and protecting against diet-induced obesity in mouse models.
International Journal of Molecular Sciences
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
A comprehensive review of the copper tripeptide GHK-Cu, documenting its modulation of thousands of human genes toward tissue remodeling, wound healing, anti-inflammatory and antioxidant activity.
Critical Care
The Efficacy of Thymosin Alpha-1 for Severe Sepsis (ETASS): a multicenter, randomized controlled trial
In 361 patients with severe sepsis, thymosin alpha-1 produced a reduction in 28-day all-cause mortality and improved monocyte HLA-DR expression, supporting its immunomodulatory role.
Current Pharmaceutical Design
Stable Gastric Pentadecapeptide BPC 157 in Trials for Inflammatory Bowel Disease and Healing
A review of the extensive preclinical literature on BPC-157, summarizing its angiogenic, cytoprotective and tendon/ligament/gut healing effects across numerous rodent injury models.
Bulletin of Experimental Biology and Medicine
Peptide Promotes Overcoming of the Division Limit in Human Somatic Cell Cultures
The Khavinson group reported that the tetrapeptide Epitalon (Epithalon) induced telomerase activity and telomere elongation in human somatic cells, allowing them to surpass the Hayflick division limit in culture.
Journal of Clinical Endocrinology & Metabolism
Prolonged Stimulation of GH and IGF-I Secretion by CJC-1295, a Long-Acting Analog of GHRH, in Healthy Adults
Single injections of CJC-1295 produced sustained, dose-dependent increases in growth hormone (2–10×) and IGF-I lasting 6+ days, with a half-life supporting once-weekly dosing.
European Journal of Endocrinology
Ipamorelin, the First Selective Growth Hormone Secretagogue
Ipamorelin stimulated growth hormone release with potency comparable to GHRP-6 but without the ACTH and cortisol elevations seen with other secretagogues, defining its selective profile.
Nature
Thymosin β4 Activates Integrin-Linked Kinase and Promotes Cardiac Cell Migration, Survival and Repair
Thymosin beta-4 (the parent of TB-500) promoted cardiomyocyte survival and migration and improved cardiac function after coronary artery ligation in mice, establishing its tissue-repair signaling.
Journal of Clinical Endocrinology & Metabolism
The Effects of a Synthetic Fragment of Human Growth Hormone (AOD-9604) on Lipid Metabolism
The C-terminal hGH fragment AOD-9604 stimulated lipolysis and inhibited lipogenesis in vitro and in obese animal models without the diabetogenic effects of intact growth hormone.
Cellular Immunology
A Comprehensive Summary of LL-37, the Factotum Human Cathelicidin Peptide
A review of LL-37, the only human cathelicidin, detailing its broad-spectrum antimicrobial activity, immunomodulation, angiogenesis and wound-healing roles.
Zh Nevrol Psikhiatr Im S.S. Korsakova
Efficacy and Safety of the Anxiolytic Selank in the Treatment of Generalized Anxiety and Neurasthenia
In a comparative clinical study, the heptapeptide Selank showed anxiolytic efficacy comparable to benzodiazepines (medazepam) without the sedation, dependence or withdrawal liabilities.
Journal of Histochemistry & Cytochemistry
Semax, an Analogue of ACTH(4-10), Increases BDNF Levels in the Rat Hippocampus
Intranasal Semax elevated BDNF and trkB expression in the hippocampus, providing a molecular basis for its reported neuroprotective and cognitive-enhancing effects.
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