SS-31
SS-31 / Elamipretide (Mitochondrial Peptide)
Mitochondria-targeting peptide studied for cellular energetics
How it works
SS-31 concentrates on the inner mitochondrial membrane where it binds cardiolipin. By stabilizing cardiolipin it is thought to protect electron-transport efficiency, reduce reactive oxygen species, and preserve ATP production under stress.
What the research explores
In published research, SS-31 has been studied in connection with the following. These describe findings reported in the literature — not approved uses, claims, or outcomes to expect.
- Targets and stabilizes mitochondrial membranes
- Studied for cellular energy (ATP) preservation
- Investigated for age-related mitochondrial decline
- Researched in heart-failure and rare mitochondrial disease
- Reduces reactive oxygen species in models
Elamipretide has been studied in clinical trials for primary mitochondrial myopathy, Barth syndrome, and heart failure, making it one of the most clinically advanced mitochondrial peptides.
Adverse events & gaps
Investigational. Injection-site reactions most commonly reported in trials. Generally well tolerated.
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