Body Composition

5-Amino-1MQ

5-Amino-1-Methylquinolinium (NNMT Inhibitor)

NNMT inhibitor researched for adipocyte metabolism and NAD+

Research Status: Preclinical; early research compound 5-Amino-1-methylquinolinium
Mechanism of Action

How it works

5-Amino-1MQ inhibits nicotinamide N-methyltransferase (NNMT), an enzyme over-expressed in fat tissue. Blocking NNMT is studied for shifting adipocyte energy metabolism and increasing cellular NAD+ availability.

Areas of Research

What the research explores

In published research, 5-Amino-1MQ has been studied in connection with the following. These describe findings reported in the literature — not approved uses, claims, or outcomes to expect.

  • Inhibits the metabolic enzyme NNMT
  • Studied for fat-cell (adipocyte) metabolism
  • Investigated for raising cellular NAD+
  • Researched for body-composition outcomes in models
  • Orally-studied small molecule
Research Highlight

Animal studies reported that NNMT inhibition reduced fat mass and improved metabolic markers without altering food intake, driving interest in 5-Amino-1MQ.

Safety Profile

Adverse events & gaps

Preclinical - human safety not established. For research use only.



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