Dihexa
Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide)
Seven orders of magnitude more potent than BDNF for cognitive enhancement
How it works
Dihexa potentiates the hepatocyte growth factor (HGF) / Met receptor signaling system, promoting synaptogenesis (synapse formation) at concentrations 10 million times lower than BDNF. This makes it potentially the most potent pro-cognitive compound ever discovered.
What the research explores
In published research, Dihexa has been studied in connection with the following. These describe findings reported in the literature — not approved uses, claims, or outcomes to expect.
- Promotes synaptogenesis and dendritic growth
- Reverses cognitive decline in Alzheimer's animal models
- Crosses the blood-brain barrier with oral bioavailability
- Potentiates HGF/Met signaling for neural repair
- Improves spatial learning and object recognition
- Neuroprotective against amyloid beta toxicity
Dr. Joe Harding's research at WSU showed Dihexa reverses cognitive deficits in aged rats to a degree never before achieved with any pharmacological agent, functioning at picomolar concentrations.
Adverse events & gaps
Unknown long-term safety profile. No human safety data. Extreme potency requires careful dose considerations.
Stay Informed on
Peptide Research
Research summaries, newly documented peptides, and clinical trial updates delivered to your inbox.
No spam. Unsubscribe at any time.