Cognitive Enhancement

Pinealon

Pinealon (Glu-Asp-Arg)

Pineal gland peptide for cognitive protection and circadian regulation

Research Status: Preclinical + limited Russian clinical studies EDR tripeptide Cortagen
Mechanism of Action

How it works

Pinealon penetrates cell nuclei and binds directly to chromatin, acting as a gene-regulatory peptide. It upregulates neuroprotective genes and has been shown to reduce free radical damage in brain tissue while supporting serotonin-melatonin rhythms.

Areas of Research

What the research explores

In published research, Pinealon has been studied in connection with the following. These describe findings reported in the literature — not approved uses, claims, or outcomes to expect.

  • Direct nuclear action to regulate neuroprotective gene expression
  • Supports circadian rhythm and sleep architecture
  • Reduces oxidative stress in neural tissue
  • Cognitive protection in aging models
  • Anti-depressant properties via serotonin modulation
  • Studied for prevention of age-related cognitive decline
Safety Profile

Adverse events & gaps

Very small size reduces immunogenicity. Well-tolerated in Russian clinical experience.



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