KPV
Lysine-Proline-Valine
Potent anti-inflammatory with gut healing and skin repair properties
How it works
KPV inhibits NF-kB activation in immune cells, blocking the production of pro-inflammatory cytokines including TNF-alpha, IL-1beta, and IL-6. It penetrates intestinal epithelial cells to directly reduce gut inflammation without systemic immunosuppression.
What the research explores
In published research, KPV has been studied in connection with the following. These describe findings reported in the literature — not approved uses, claims, or outcomes to expect.
- Potent anti-inflammatory via NF-kB inhibition
- Heals inflammatory bowel conditions (Crohn's, UC models)
- Wound healing and skin regeneration
- Anti-microbial properties
- Reduces cytokine storm without systemic immunosuppression
- Effective orally due to stability in GI tract
KPV demonstrates remarkable efficacy in colitis models, reducing inflammation by over 70% compared to controls, with oral bioavailability that makes it uniquely practical among anti-inflammatory peptides.
Adverse events & gaps
Considered very safe. Small size and natural origin reduce immunogenicity risk.
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